Benzo[b]thiophene-2-methanol, 5-bromo-
(5-Bromo-benzo[b]thiophen-2-yl)-methanol
CAS: 13771-72-7
Molecular Formula: C9H7BrOS
Benzo[b]thiophene-2-methanol, 5-bromo- - Names and Identifiers
Benzo[b]thiophene-2-methanol, 5-bromo- - Physico-chemical Properties
| Molecular Formula | C9H7BrOS |
| Molar Mass | 243.12 |
| Density | 1.699±0.06 g/cm3(Predicted) |
| Boling Point | 379.9±27.0 °C(Predicted) |
| pKa | 13.69±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD12032279 |
Benzo[b]thiophene-2-methanol, 5-bromo- - Risk and Safety
| Hazard Class | IRRITANT |
Benzo[b]thiophene-2-methanol, 5-bromo- - Introduction
(5-Bromo-benzo [B] thiophen-2-yl)-methanol ((5-bromobenzothiophen-2-yl)-methanol) is an organic compound with the following properties:
1. Appearance: White crystalline solid at room temperature.
2. chemical formula: C10H7BrOS.
3. Molecular weight: 259.14g/mol.
(5-Bromo-benzo [B] thiophen-2-yl)-methanol have many uses in organic synthesis, such:
1. Intermediate: It can be used as an intermediate in organic synthesis and used in the synthesis of other organic compounds.
2. Drug research: The compound is widely used in drug research in the field of medicinal chemistry, especially for antibacterial and anticancer activities.
The preparation method of the compound can be synthesized through the following steps:
1. 2-Bromobenzothiophene (2-Bromo-benzo [B] thiophene) was first prepared.
2. reacting 2-bromobenzothiophene with borate and palladium catalyst to prepare (5-Bromo-benzo [B] thiophen-2-yl)-boronic acid.
3. Finally, (5-Bromo-benzo [B] thiophen-2-yl)-boronic acid is reacted with methanol to obtain the target product (5-Bromo-benzo [B] thiophen-2-yl)-methanol.
When using or handling this compound, you need to pay attention to the following safety information:
1. toxicity: the compound may be toxic to human body. Direct contact with skin, eyes or respiratory system should be avoided.
2. fire risk: the compound may burn under the fire source, the release of toxic gases.
3. storage conditions: should be stored in a dry, cool place, and avoid contact with oxidants.
4. Waste treatment: The used compounds should be treated in accordance with local laws and regulations to avoid pollution to the environment.
Please note that safety procedures should be strictly followed when using or handling any chemical substance, and refer to the safety data sheet (SDS) of the compound for more detailed information.
1. Appearance: White crystalline solid at room temperature.
2. chemical formula: C10H7BrOS.
3. Molecular weight: 259.14g/mol.
(5-Bromo-benzo [B] thiophen-2-yl)-methanol have many uses in organic synthesis, such:
1. Intermediate: It can be used as an intermediate in organic synthesis and used in the synthesis of other organic compounds.
2. Drug research: The compound is widely used in drug research in the field of medicinal chemistry, especially for antibacterial and anticancer activities.
The preparation method of the compound can be synthesized through the following steps:
1. 2-Bromobenzothiophene (2-Bromo-benzo [B] thiophene) was first prepared.
2. reacting 2-bromobenzothiophene with borate and palladium catalyst to prepare (5-Bromo-benzo [B] thiophen-2-yl)-boronic acid.
3. Finally, (5-Bromo-benzo [B] thiophen-2-yl)-boronic acid is reacted with methanol to obtain the target product (5-Bromo-benzo [B] thiophen-2-yl)-methanol.
When using or handling this compound, you need to pay attention to the following safety information:
1. toxicity: the compound may be toxic to human body. Direct contact with skin, eyes or respiratory system should be avoided.
2. fire risk: the compound may burn under the fire source, the release of toxic gases.
3. storage conditions: should be stored in a dry, cool place, and avoid contact with oxidants.
4. Waste treatment: The used compounds should be treated in accordance with local laws and regulations to avoid pollution to the environment.
Please note that safety procedures should be strictly followed when using or handling any chemical substance, and refer to the safety data sheet (SDS) of the compound for more detailed information.
Last Update：2024-04-09 21:21:28
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